There is no disputing the tremendous benefits of exercise, however is there a safest time of day to exercise? As seen in publicly reported events such as marathons and professional sports, there is paradoxically a slight increased risk of myocardial infarction and sudden cardiac death (SCD) during vigorous activity.
Biological processes in living organisms that oscillate with a periodicity of 24 hours are referred to as circadian. The incidence of SCD is influenced by circadian rhythm. Retrospective analyses of the Framingham Heart Study and Milwaukee Paramedics have shown an increased risk of having an event between 6am-12pm and 7am-9am respecitvely. For healthy persons who exercise regularly at high intensities it is unclear whether circadian rhythms have the same influence on MI and SCD as they do in the general population.
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